I'm not a scientic and I'm new at this, but I want to help. Can someone tell me in plain english what work my computer is doing for Rosseta (CPU is runnig 100% all the time), also is there any estimate how much work must be done to finish whatever we are doing?

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I do not really have an idea what they write there :

http://www.boinc.cz/view.php?cisloclanku=2005121901

but I guess it is what you are looking for :-)


p.s.: Honza knows much about everything related to BOINC and BOINC projects so he is always a good source for informations.

Thanks buddy, great site. I think I'll join Czech National Team :-)))

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...is there any estimate how much work must be done to finish whatever we are doing?

Welcome to Rosetta!

Right now, the immediate task is to apply the techniques that Dr. Baker's team have developed to the CASP. The assessment of how the technology is improving over time.

After that is complete, next week I believe is the last deadline for submission, they will probably return to study of the Rosetta techniques as compared to known protein structures. There are too many proteins to define an end to the work. The idea here is to learn enough about them so as we can accurately predict what they look like (i.e. what shape they take), without using the existing technology for doing so, which is too slow and costly.

The project will also be studying "docking". That is, which proteins or chemical compounds will "fit" with a given protein. If a protein chain is found in this year's flu virus for example, then docking with it might be a potential treatment of that virus. And so Rosetta will be used to predict which compunds would dock the best, or dock exclusively to the flu virus. Once you know that, you can go about "design", which would be to artificially build the new protein cure.

In a nutshell, the study of proteins is in the basic scientific reasearch stage. As new ideas are applied to the problem, Rosetta@home can be used to test there validity. Can we arrive at the right answer with this new idea? Can we arrive an the answer faster? Can we combine this with other ideas and devise an approach which is even better? These are the basic questions, and all of us are helping to answer them as we crunch Rosetta.

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Running Microsoft's "System Idle Process" will never help cure cancer, AIDS nor Alzheimer's. But running Rosetta@home just might!
https://boinc.bakerlab.org/rosetta/