The Protein folding revolution!

Message boards : Rosetta@home Science : The Protein folding revolution!

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krypton
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Message 80412 - Posted: 22 Jul 2016, 6:16:10 UTC
Last modified: 22 Jul 2016, 6:17:52 UTC

The protein folding effort we've been working on has been featured in Science:

http://science.sciencemag.org/content/353/6297/338.full

They also made a youtube video:
https://www.youtube.com/watch?v=cAJQbSLlonI

BOINC and Rosetta@home was heavy used for this work, thanks for all the contributions!

“We didn't [cheat],” Sergey Ovchinnikov, a grad student in Baker's lab, says with a chuckle.

-krypton (aka Sergey)
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Message 80444 - Posted: 27 Jul 2016, 23:13:14 UTC

Awesome :)

Haven't watched to vid yet but will in the morning...
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Message 80457 - Posted: 1 Aug 2016, 13:23:31 UTC

Watched the video, it's super accessible to lay people and does a great job of highlighting a huge swath of what Rosetta does and in particular the co-evolution 'shortcut' that you've been working so much on Sergey - big congrats!

Are you using co-evolution predictions in this year's CASP? I remember it being quite successful in CASP11.

I'd be curious to learn if/how there has been any iterative refinement of the methodology since CASP11?

PS - You and David are the most engaged baker lab members on the boards here, thanks for taking the time to post and keep us in the loop. :)
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Message 80460 - Posted: 1 Aug 2016, 21:31:45 UTC - in response to Message 80412.  

Watched the video and it is amazing to see what has been accomplished in such a short period of time. The potential is unlimited and the vision is glorious. I am excited to see what the future holds!

Bill
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Message boards : Rosetta@home Science : The Protein folding revolution!



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